DoseDistrict

Testosterone Replacement Therapy

Testosterone replacement therapy (TRT) is used for some men with diagnosed hypogonadism. The Endocrine Society recommends identifying compatible symptoms together with consistently low testosterone levels on appropriate testing. Fatigue alone does not establish a diagnosis.

Diagnosis and monitoring

Ask about repeat morning testing, investigation of the cause and a follow-up plan. Monitoring can include testosterone and hematocrit, with prostate risk assessment when appropriate. Discuss fertility before starting because testosterone therapy can suppress sperm production.

Compare care and costs

Ask about the specific formulation, transfer precautions for topical products, supplies for injections, and who handles out-of-range results. Request an itemized price for labs, medication, follow-up and shipping before committing.

Endocrine Society guideline